The antigenicity of the major outer membrane protein of Chlamydia trachomatis serovar C
was assessed by using overlapping hexapeptide homologs of serovar C major outer
membrane protein and rabbit antisera in a peptide enzyme-linked immunosorbent assay.
Five immunogenic sites were found distributed within variable sequences of the protein: four
were immunodominant and three were surface exposed on native elementary bodies of
serovar C. None was surface exposed on serovars H, I, and J.